منابع مشابه
Is heparin reversal with protamine after carotid endarterectomy dangerous?
OBJECTIVE Although systemic heparinisation is routine during CEA, reversal with protamine is controversial with 3 studies suggesting increased peri-operative stroke rates and 3 no effect. None included independent peer-review. DESIGN Non-randomised observational study of data derived from a randomised controlled study of anaesthetic technique for CEA. METHODS Data on heparin and protamine u...
متن کاملHeparin induced thrombocytopenia
Abstract Background and Objectives Heparin is still a commonly used anticoagulant in prophylaxis and treatment of thromboembolic events. Heparin-induced thrombocytopenia (HIT) is a life-threating adverse drug reaction of heparin. The diagnosis of HIT is made based on two important criteria, firstly clinical evaluation and secondly laboratory testing. In this comprehensive review, the authors w...
متن کاملAn Extended Link Reversal Protocol in Dynamic Networks
We consider the problem of maintaining routing paths between nodes in a dynamic network. Gafni and Bertsekas proposed a link reversal approach called the BG method that maintains a directed acyclic graph (DAG) with a given destination as the sink node. By virtue of built-in redundancy, an updating algorithm to establish a new DAG is activated infrequently and it happens only when the last outgo...
متن کاملEmergency reversal of heparin overdose in a neurosurgical patient guided by thromboelastography.
Editor—Reversing heparin-induced anticoagulation quickly and effectively can be challenging in bleeding patients undergoing emergency surgery. The required dose of protamine to neutralize unfractionated heparin (UFH) is difficult to predict and use of standard coagulation tests such as activated partial thromboplastin time (aPTT) to assess the effectiveness of reversal may delay surgery, compro...
متن کاملAbsence of complement-mediated events after protamine reversal of heparin anticoagulation.
Protamine reversal of heparin anticoagulation is associated with adverse hemodynamic effects that may be attenuated with protamine pretreatment (PP). This study assesses the role of complement activation during these phenomena in adult cardiac surgery patients. Sixteen individuals undergoing cardiopulmonary bypass were given intravenous normal saline or protamine (2 mg/kg) as a randomized pretr...
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ژورنال
عنوان ژورنال: Canadian Journal of Anaesthesia
سال: 1989
ISSN: 0832-610X,1496-8975
DOI: 10.1007/bf03011452